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Lennox-Gastaut syndrome (LGS) is a severe form of childhood epilepsy that is defined by generalized multiple types seizures, slowness of intellectual growth, and a specific electroencephalogram disturbance. Which of the following cannabinoids is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome?

A. Nabiximols

B. Nabilone

C. CBD

D. Cannabis

E. THC

Answer: C

THC and CBD are the two primary substances found in cannabis. Nabiximols (Sativex) is extracted THC/CBD used to treat advanced cancer pain, Multiple Sclerosis neuropathic pain or spasticity; Nabilone (Cesamet) is THC analog used to treat severe nausea and vomiting due to cancer chemotherapy, AIDS-related anorexia, palliative pain, and neuropathic pain.

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PEBC Exam Practice Questions

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A 55-year-old patient with Type 2 diabetes mellitus is non-compliant with medication and diet recommendations. The simplest and informative way to assess for past non-compliance and long-term glycemic control would be to perform which of the following tests?

A. Fasting blood glucose test
B. Glucose tolerance test
C. Glycated hemoglobin test
D. Urine ketone test

Answer: C

Glycated hemoglobin or A1C test identifies the three-month average plasma glucose concentration. The test is limited to a three-month average because the maximum lifespan of a red blood cell is 120 days.

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